Skip Navigation

Neuro-Oncology 2008 10(3):361-367; doi:10.1215/15228517-2008-008
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrowScopus Links
Google Scholar
Right arrow Articles by Brandes, A. A.
Right arrow Articles by Franceschi, E.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Brandes, A. A.
Right arrow Articles by Franceschi, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Copyright 2008 by the Society for Neuro-Oncology

Disease progression or pseudoprogression after concomitant radiochemotherapy treatment: Pitfalls in neurooncology

Alba A. Brandes, Alicia Tosoni, Federica Spagnolli, Giampiero Frezza, Marco Leonardi, Fabio Calbucci and Enrico Franceschi

Departments of Medical Oncology (A.A.B., A.T., E.F.), Radiotherapy (F.S., G.F.), Neuroradiology (M.L.), and Neurosurgery (F.C.), Bellaria-Maggiore Hospital, AUSL Bologna, Bologna, Italy

Address correspondence to Alba A. Brandes, Department of Medical Oncology, Azienda USL Bellaria-Maggiore, Bologna, Italy (alba.brandes{at}yahoo.it).


  Abstract

Although radionecrosis has been exhaustively described in depth in the neurooncological literature, its diagnosis is still a challenging issue because its radiological pattern is frequently indistinguishable from that of tumor recurrence. This review discusses the causes of radionecrosis and the potential effect of adjuvant chemotherapy concomitant with radiotherapy on its rate and onset. The potential pitfalls in clinical studies attempting to make a differential diagnosis between radionecrosis and disease progression are also discussed.

Keywords: chemotherapy, glioma, pseudoprogression, radionecrosis, radiotherapy

Received March 5, 2007; Accepted June 10, 2007


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 JCOHome page
A. A. Brandes, E. Franceschi, and A. Tosoni
In Reply
J. Clin. Oncol., September 10, 2008; 26(26): 4359 - 4360.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.